Location: St Laurent (Exhibits)

	Peggi Angel, PhD MUSC Proteomics Center Peggi Angel is Associate Professor at Medical University of South Carolina, where she works on technology advancements in MALDI imaging mass spectrometry (IMS) and biomarker imaging analyses in cancer disparities. Dr. Angel attended graduate school at the University of Georgia’s Complex Carbohydrate Research Center, graduating with a PhD in 2007. Her graduate research was on development of technologies for mapping N-linked glycan sites in mammalian development. After a postdoctoral fellowship at Emory University focused on membrane proteomics of fetal alcohol syndrome, she won a competitive Postdoctoral Fellowship with the Systems-based Consortium for Organ Design and Engineering. With the Fellowship, she worked at Vanderbilt University in the laboratory of Richard Caprioli on methods using MALDI IMS for developmental biology. Dr. Angel has developed IMS methods for increasing sensitivity of protein detection from tissues, analysis and identification of signaling lipids in negative mode, targeted metabolomics on tissue and cell culture, extracellular matrix protein detection in FFPE tissues, and N-glycomic strategies for proteins, cells, and tissue. Dr. Angel is a co-founder of Glycopath, a company that focuses on glycosylation patterns as a prognostic or diagnostic tool. She serves on the board of N-Zyme Scientifics, a company that produces enzymes for mass spectrometry. Dr. Angel is committed to serving the imaging mass spectrometry community and serves as President-Elect for the US Imaging Mass Spectrometry Society.
	Emma Guiberson, PhD Middlebury College Emma completed her B.S. in Chemistry and Philosophy at the University of Notre Dame, conducting research in organic chemistry and chemistry education research, before pursuing a PhD in Chemistry at Vanderbilt University. As a graduate student in the labs of Dr. Richard Caprioli and Dr. Jeff Spraggins, her research focused primarily on the application of imaging mass spectrometry to the gastrointestinal tract (Guiberson, et. al. JASMS 2022) and utilizing targeted small molecule analysis to better study bile acids in the gastrointestinal tract during Clostridioides difficile infection (Wexler and Guiberson, et. al. Cell Reports 2021). Additionally, she worked on utilizing spatial proteomics to understand abscess formation during Staphylococcus aureus infections (Guiberson and Weiss, et. al. ACS Infectious Diseases 2020). This work led to an interest in the gut microbiome and the metabolites produced by microbes in the gastrointestinal tract. After defending her PhD in August of 2022, Emma then joined the lab of Dr. Justin Sonnenburg at Stanford University to study microbial-derived metabolites. Her current work in the Sonnenburg lab focuses on both untargeted metabolomics using a library of microbiome-derived metabolites (Han, Guiberson, Sonnenburg, Protocol Exchange, 2022), as well as necessary targeted methods for quantitative analyses of metabolites of interest that accumulate as uremic toxins during kidney disease. Emma has since started her independent career at Middlebury College investigating the metabolome of the oral microbiome during oral disease.
	Emily Harari, BS Artyc PBC Based on a foundation of early wetlab experience, I've worked in both large pharma and small biotech. My experience is in study operations and I'm currently focused on solving the problem of reliable specimen handling in decentralized trials and point-of-care testing. I'm interested in reducing pre-analytical errors and maximizing sample quality using reliable temperature control and other safe-handling practices of specimens in transit to the lab.

Table TBA: Multi-omics by the MS Imaging Platform : What's new and what's needed?

Peggi Angel

Table TBA: Undergraduate Research in Mass Spectrometry: How to make our labs more undergraduate friendly.

Emma Guiberson

More and more industries are looking for graduates trained in mass spectrometry, even at the bachelors level. Training our undergraduate population in these technologies is important now more than ever, yet requires a very different approach than graduate students. How do we best prepare our undergraduates for both industry and academic experiences using MS? What systems do we need in place within our labs to both support these students, and ensure consistency in data collection, analysis, and reporting? How do we keep these systems in place with the high rates of turnover in undergraduate researchers compared to graduate students? This brainstorming and networking roundtable will address these questions and share positive and negative experiences that can help inform groups including undergraduates moving forward.

Table TBA: Patient centric remote sampling for clinical diagnostics – How do we integrate these samples with existing (non-MS) laboratory workflows?

Emily Harari, Shelley Hossenlopp, Enaksha Wickremsinhe, Dajana Vuckovic, Russell Grant

Numerous technologies are now commercially available that facilitate the collection of human blood samples in locations away from the clinical setting. This approach is termed patient centric sampling, or microsampling and can involve the collection of samples from a finger stick, or from elsewhere on the body. The samples can be dried, or liquid and are often a smaller volume than those obtained by traditional phlebotomy.

The use of these approaches potentially enables samples to be collected from currently underserved communities (pediatric, elderly, remote areas, etc). Furthermore, the approach may enable more regular sampling of individuals to be performed and facilitates choice for the patient about how and where samples will be collected. These technologies also have the potential to overcome the discomfort, pain and fear that is encountered by many when collecting samples by traditional phlebotomy. However, the format of samples collected this way is often different to those routinely analyzed in the clinical laboratory, i.e. small volume, whole blood, dried blood, particularly for non LC/MS based assays. Participants of this workshop will take part in a facilitated discussion on what the challenges are in the clinical laboratory to the adoption of these technologies and will then focus on how they might be overcome and what future activities might be required to enable this.

Table TBA: Women in Laboratory Leadership Roles

Stacy Beal

This discussion will focus on the importance and impact of women in leadership roles within the laboratory. Despite the increasing representation of women in healthcare, leadership positions remain disproportionately occupied by men. This discussion aims to highlight the barriers women face in advancing to leadership roles, such as gender bias, lack of mentorship, and work-life balance challenges. Additionally, we will discuss the critical value women bring to laboratory leadership, including diverse perspectives, empathy, and innovative approaches to patient care and organizational management. We will examine strategies for fostering gender equity in leadership, including mentorship programs, organizational support for work-life integration, and policies aimed at addressing unconscious bias. Furthermore, we will explore the role of male allies in advancing these efforts and the importance of creating inclusive environments that allow women to thrive in senior roles. Through this discussion, we will propose actionable insights and recommendations.

Table TBA: Ensuring Statistical Power in Biomarker Discovery in Assay Development

Tim Collier

Table TBA: Multi-Analyte QC

Stephen Master, Russ Grant

Location: St Laurent (Exhibits)

Location: St Laurent (Exhibits)

Location: Salon Ville-Marie, Hotel Level

Closing statements and poster awards.

Location: Salon Ville-Marie, Hotel Level