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MSACL Workshop

MSACL 2017 EU Corporate Workshop

Agilent Technologies

PRE-REGISTER for this Workshop

Time:16:00 - 16:30

Multiplexed Proteomic Analysis – The Need for Speed without Compromises
Dr. Cory Bystrom, VP of Research and Development Clevland Heart Laboratory

High density lipoprotein (HDL) plays a number of roles in vascular biology, including lipid and cholesterol transport, anti-oxidative and anti-thrombotic activity, endothelial regulation, and immune response regulation. Cholesterol efflux capacity (CEC), the transport of intracellular cholesterol from macrophages to an accepting HDL particle. The CEC assay is a challenging cell based assay that is labor intensive and low throughput. To enable research investigating CEC and its role in atherosclerotic plaque development we have developed a multiplex proteomic approach to estimating cholesterol efflux from a measurement of six lipoproteins.