|08:00 - 08:45
Measurement of Eicosanoids and their Urinary Metabolites using Mass Spectrometry
Ginger L. Milne, PhD, Research Associate Professor, Director, Eicosanoid & Neurochemistry Core Laboratories, School of Medicine, Vanderbilt University, TN
Eicosanoids are important signaling molecules central to many critical physiological processes such as inflammation, pregnancy and childbirth, and cardiovascular function. Dysregulation of eicosanoid production has been implicated in a number of diseases such as oncology, metabolic syndrome, and cardiovascular disease. Derived by the enzymatic or non-enzymatic oxidation of arachidonic acid or other 20 carbon length polyunsaturated fatty acids (PUFAs), eicosanoids are challenging to quantitatively measure due to their inherent structural and chemical similarities. This workshop will demonstrate how targeted mass spectrometry workflows are key to accurate and precise measurement of eicosanoids for clinical research and why they are required to further biomedical research of these important class of biochemicals.
For Research Use Only. Not for use in Diagnostic Procedures.