LC-MSMS 101 : Getting Started with Quantitative LC-MSMS in the Diagnostic Laboratory
Location: Montreal 1-2
830
1230
LC-MSMS 203 : Validation of Quantitative LC-MS/MS Assays for Clinical and Academic Use
Location: Montreal 3
Claire Knezevic, PhD
Lurie Childrens Hospital
Dr. Claire Knezevic is a clinical chemist in the Department of Pathology and Laboratory Medicine at Lurie Children's Hospital with a focus on chemistry, point-of-care testing, quality improvement, drug monitoring, and personalized medicine. She is an Associate Professor in Northwestern's Feinberg School of Medicine in the Department of Pathology. Her interests include all things small molecule, from toxicology to therapeutic drug monitoring and their impacts on clinical care.
Joshua Hayden, PhD, DABCC, FACB
Norton Healthcare
Joshua is currently the Chief of Chemistry at NortonHealthcare. He earned his PhD in chemistry from Carnegie Mellon University. He conducted postdoctoral research at Massachusetts Institute of Technology before completing a two-year clinical chemistry fellowship at University of Washington and 4 years as Assistant Professor at Weill Medical College. Joshua has special expertise developing and overseeing mass spectrometry assays in the clinical laboratory.
830
1230
Glyco(proteo)mics 101 : Clinical Glyco(proteo)mics by Mass Spectrometry
Location: Westmount 5
Guinevere Lageveen-Kammeijer, PhD
University of Groningen
Dr. Guinevere Lageveen-Kammeijer is an Assistant Professor in the Analytical Biochemistry group at the University of Groningen, within the Groningen Research Institute of Pharmacy. She holds a BSc in Biotechnology - Forensic Sciences from the University of Applied Sciences van Hall Larenstein, Leeuwarden, and an MSc in Analytical Chemistry from VU University, Amsterdam. Her research interests were ignited during her MSc internship, where she focused on separation techniques coupled with mass spectrometry.
Guinevere earned her PhD in Clinical Glycomics from the Leiden University Medical Center in 2019 under the supervision of Prof. Manfred Wuhrer. Her thesis developed small-scale sample preparation workflows using capillary electrophoresis (CE) and mass spectrometry (MS/MS) to analyze glycans, glycopeptides, and glycoproteins, with applications in biomarker discovery and biopharmaceutical characterization. She continued her research as a post-doctoral researcher at the same institution before expanding her expertise with a visit to Northeastern University, Boston, in 2017, where she focused on protein charge and proteoform heterogeneity.
In 2022, Guinevere began her tenure-track assistant professorship at the University of Groningen, where she works on advancing glyco(proteo)mic techniques, particularly in single-cell glycomic analysis. Her research includes expanding the mass spectrometry-based glycosylation assay for prostate-specific antigen (PSA), a key biomarker for prostate cancer, and exploring the in-depth analysis of glycans and glycoproteins for biomarker discovery in other diseases and biopharmaceutical characterization.
Guinevere’s contributions have been recognized through funding such as the Investigator Sponsored Research grant from Astellas (2019) and the prestigious NWO VENI grant (2023). She is actively involved in the scientific community, serving on the Scientific Omics Committee for MSACL. Guinevere is passionate about promoting the importance of glycosylation in biomarker research, aiming to bridge the gap between researchers and clinical professionals to improve biomarker translation to the clinic.
Tamás Pongrácz, PhD
Karolinska Institutet;
Leiden University Medical Center
Tamas Pongracz is an analytical chemist who, during his PhD and postdoctoral training at Leiden University Medical Center in the Netherlands, specialized in developing and refining advanced analytical methods and bioinformatics tools for high-throughput mass spectrometry-based protein glycosylation analysis.
His research focuses on exploring the glycomic dimensions of human diseases, establishing links between antibody structure and function, and contextualizing these findings within clinical disease proxies across various conditions. Currently he works as a postdoctoral researcher in the group of Charlotte Thalin at Karolinska Institute, Sweden, where his research focuses on the role of secretory IgA glycosylation in mucosal immunity.
Tamas' primary ambition is to introduce a next-generation, noninvasive liver fibrosis marker to the clinical lab by bridging the gap between his basic research findings and practical application.
830
1230
Automation 201 : Streamlining Clinical Analysis through Efficient Workflow Integration
Location: Westmount 6
Evan McConnell, PhD
Labcorp
Matthew Campbell, PhD
Labcorp
830
1230
Clinical Proteomics 201 : Clinical Proteomics
Location: Outremont 1
Andy Hoofnagle, MD, PhD
University of Washington
Dr. Hoofnagle's laboratory focuses on the precise quantification of recognized protein biomarkers in human plasma using LC-MRM/MS. In addition, they have worked to develop novel assays for the quantification of small molecules in clinical and research settings. His laboratory also studies the role that the systemic inflammation plays in the pathophysiology of obesity, diabetes, and cardiovascular disease.
Cory Bystrom, PhD
Ultragenyx
Christopher Shuford, PhD
Labcorp
Chris Shuford, Ph.D., is Associate Vice President and Technical Director for research and development at Laboratory Corporation of America in Burlington, North Carolina. Chris received his B.S. in Chemistry & Physics at Longwood University and obtained his Ph.D. in Bioanalytical Chemistry from North Carolina State University under the tutelage of Professor David Muddiman, where his research focused on applications of nano-flow chromatography for multiplexed peptide quantification using protein cleavage coupled with isotope dilution mass spectrometry (PC-IDMS). In 2012, Chris joined LabCorp’s research and development team where his efforts have focused on development of high-flow chromatographic methods (>1 mL/min) for multiplexed and single protein assays for clinical diagnostics.
830
1230
Data Science 203 : Machine Learning : A Gentle Introduction
Location: Outremont 3
830
1230
Data Science 101 : Breaking Up with Excel
Location: Outremont 4
830
1230
LC-MSMS 302 : Advanced LC-MSMS Method Development, Troubleshooting and Operation for Clinical Analysis
Location: Outremont 5
1230
1430
Lunch Break
Location: Your Choice
1430
1830
LC-MSMS 101 : Getting Started with Quantitative LC-MSMS in the Diagnostic Laboratory
Location: Montreal 1-2
1430
1830
LC-MSMS 203 : Validation of Quantitative LC-MS/MS Assays for Clinical and Academic Use
Location: Montreal 3
1430
1830
Data Science 100 : Data Literacy
Location: Westmount 2
1430
1830
Glyco(proteo)mics 101 : Clinical Glyco(proteo)mics by Mass Spectrometry
Location: Westmount 5
1430
1830
Automation 201 : Streamlining Clinical Analysis through Efficient Workflow Integration
Location: Westmount 6
1430
1830
Clinical Proteomics 201 : Clinical Proteomics
Location: Outremont 1
1430
1830
Data Science 203 : Machine Learning : A Gentle Introduction
Location: Outremont 3
1430
1830
Data Science 101 : Breaking Up with Excel
Location: Outremont 4
1430
1830
LC-MSMS 302 : Advanced LC-MSMS Method Development, Troubleshooting and Operation for Clinical Analysis
Location: Outremont 5
1430
1830
Isotopes 101 : Modern Isotope Ratio Analysis for Biomedical Research and Clinical Diagnostics
Location: Outremont 6
Cajetan Neubauer
University of Colorado, Boulder
The frontiers of metabolomics & proteomics are finally merging with isotope ratio mass spectrometry, opening exciting new opportunities in our understanding of biological systems.
My lab at the University of Colorado Boulder helps pioneer related novel molecular measurements based on soft-ionization isotope ratio mass spectrometry. These advances can be used to study natural stable isotope fingerprints in metabolites, drugs, or small inorganic ions for a fascinating range of cross-disciplinary applications in life and earth sciences.
To achieve our longterm goal of making natural isotope patterns universally useful, we combine expertise in metabolomics and proteomics with advanced concepts of high precision stable isotope analysis from geochemistry.
Dwight Matthews, Ph.D.
University of Vermont
Prof. Matthews received his PhD degree in 1977 in Analytical Chemistry from Indiana University with a focus in mass spectrometry. For his Ph.D. thesis he developed the first gas chromatograph-combustion-isotope ratio mass spectrometer (GC-C-IRMS). He then began his career at Washington University School of Medicine in St. Louis in the Department of Medicine where he developed stable isotope tracer methods to study in vivo amino acid metabolism in humans centered around gas chromatography-mass spectrometry (GC-MS). Several of these methods are commonly used by investigators today. In 1986 he moved to Cornell University Medical College in New York City as a tenured Associate Professor of Biochemistry in Medicine and Surgery to continue studies of metabolism. Here his focus broadened to include studies of metabolism in conditions found commonly in surgical metabolism and energy metabolism using doubly labeled water measured by IRMS. He also directed the Core Laboratories of the General Clinical Research Center. In 1996 he moved to the University of Vermont (UVM) as a Professor of Medicine in the College of Medicine and as a Professor of Chemistry in the College of Arts and Sciences. At UVM he directed core laboratories related to mass spectrometry for the Clinical Research Center, the Vermont Genetics Network Proteomics Core Laboratory, and the Mass Spectrometry Core Laboratory in Immunobiology. During this period, he developed new proteomics methods using liquid chromatography-mass spectrometry (LC-MS) with a focus on precise measurement of stable isotopic enrichments in proteins and peptides. From 2002-2014, he was Chair of the Department of Chemistry at UVM and named the Pomeroy Professor of Chemistry. In 2019, Matthews became a Professor Emeritus of Chemistry and Medicine at UVM, but continues his research activities. Professor Matthews is a world-renown expert in the development of stable isotope tracer techniques to study metabolism in humans. He has published over 175 papers in a range of peer-reviewed journals and over 75 contributions to symposia and chapters in books, and has an H-index of 85.
Patrick Day, MPH, MLS (ASCP)
Mayo Clinic
My background, training, and educational degrees are in Laboratory Medicine & Pathology and Public Health. I received my bachelor’s and master’s degrees both from the University of Minnesota. My MPH thesis was on how geospatial supercomputing and clinical laboratory data can be combined to study how socioeconomic determinants of health and geography within the United States are associated with elevated levels of arsenic and mercury in humans. I am currently a principal developer in the Division of Computational Pathology and Artificial Intelligence at the Mayo Clinic in Rochester, MN. Prior to this role, I was a senior developer with the Metals Laboratory at Mayo Clinic. This clinical laboratory is staffed by thirty highly specialized employees that conduct metal analysis of biologic samples as well as analyze thousands of kidney stones a year by Fourier Transform Infrared Spectroscopy (FTIR). In the Metals Laboratory, I developed numerous laboratory developed tests (LDTs) as well as managed various multidisciplinary research projects. I currently hold the academic rank of Instructor in the Mayo Clinic College of Medicine and Science. I have co-authored numerous conference abstracts and peer-reviewed articles related to metals toxicology and artificial intelligence in the clinical laboratory and was honored to receive an American Society for Clinical Pathology 40 under Forty award.
1430
1830
Lipidomics 101 : Mass Spectrometry-based Lipidomics and Clinical Applications
Location: Outremont 7
Anne K. Bendt, PhD
Singapore Lipidomics Incubator (SLING), National University of Singapore
Anne K Bendt studied Biology focusing on marine biotechnology (Greifswald University, Germany), followed by a PhD in Biochemistry (Cologne University, Germany) employing proteomics and transcriptomics. Driven by her fascination for infectious diseases, she joined the National University of Singapore (NUS) in 2004 to develop lipidomics tools for tuberculosis studies. She is now a Principal Investigator at the Life Sciences Institute, NUS, focussing on translation of mass spec technologies into clinical applications, and serving as the Deputy Director of the Singapore Lipidomics Incubator (SLING) taking care of operations and commercialization.
Amaury Cazenave Gassiot, PhD
Singapore Lipidomics Incubator (SLING) and Department of Biochemistry, National University of Singapore
Research Assistant Prof. Cazenave-Gassiot is an early-career researcher and an expert in mass spectrometry-based lipidomics. He graduated with a PhD in analytical chemistry at the University of Southampton (UK), under the supervision of Dr John Langley, specialising in supercritical fluid chromatography and mass spectrometry. His interest in lipids started while a postdoc in the team of Professor Anthony Postle, still in Southampton. A member of SLING since 2009, his research centres on separation sciences, mass spectrometry, and their applications to life sciences, especially lipid biochemistry. He has developed chromatographic and mass spectrometric methods for the identification and quantification of lipids in diverse biological systems. This has included successful local and international collaborations.
Michael Chen, MD MSc
The University of British Columbia
Dr. Michael Chen is a clinical pathologist, specializing in clinical chemistry and translational mass spectrometry. He is the Division Head of Medical Biochemistry at Island Health and Provincial Discipline Lead at Provincial Health Services Authority. As a researcher, Dr Chen is the scientific director of UBC Translational Omics Lab in the Victoria General Hospital. He is also the director of Vancouver Island Biobank, and he co-chairs the BC Biobank Network. Dr. Chen’s research focuses on clinical mass spectrometry, biobanking, biomarker validation and clinical implementation.
1830
1900
Happy Half-Hour!
Location: Foyer, Conference Level
Open to all conference registrants.
1900
2100
Dinner
Location: Your Choice
1900
2300
Waters Private Event
Location: Salon Bonaventure, Hotel Level
2100
2330
MSACL Hospitality Lounge
Location: Salon Ville-Marie, Hotel Level
Open to all conference registrants.
Network with colleagues. Drinks and snacks provided.
