User Group Meetings

Tuesday Evening
7:00 - 8:30+ PM

Pre-Register for this User Group
New Application Seminar - Mass Spectrometric Immunoassays (MSIA) - The evolution of targeted MS workflows and platforms
Dr. Eric Niederkofler, Dr. Lewis Couchman, Dr. Benoit Coulombe, Dr. Chegjie Ji

Speakers will describe the applications & advantages of Thermo Scientific MSIA (Mass Spectrometric Immunoassay) workflows. MSIA workflows are comprehensive and customizable targeted-MS based approaches that combine highly selective sample interface preparation with MS for simultaneous qual/quan analysis. Dr. Niederkofler will define the MSIA workflows and technologies. Dr. Couchman will highlight reproducible and high-throughput methods for intact insulin and its therapeutic analogs from donor samples by using MSIA with high-resolution accurate mass (HRAM) MS instrumentation. Dr. Ji will discuss a new approach to detect low-level protein, TNFa. The speakers will participate in a panel discussion, hosted by Dr. Coulombe, to provide further insight into MSIA applications and how new users can quickly adopt MSIA workflows in their labs.

MALDI Imaging Mass Spectrometry: Technical Advances and Clinical Problem Solving
Jeremy L. Norris, National Research Resource for Imaging Mass Spectrometry,Vanderbilt University School of Medicine

MALDI Imaging Mass Spectrometry (IMS) is a unique technology that combines the spatial advantages of microscopy with the chemical specificity of modern mass spectrometers. The combination of these advantages can be leveraged to investigate biological systems of clinical importance (e.g., tissues). Recent advances in MS instrumentation, sample preparation methods, and biocomputational approaches to image analysis are converging to enable novel, clinically important applications of IMS. Advances emerging from collaboration between the National Research Resource for Imaging Mass Spectrometry, Department of Biochemistry, Vanderbilt University School of Medicine and SimulTOF Systems will be discussed by key personnel from both organizations.

(1) New sensitivity and selectivity gains with the QTRAP 6500® system and SelexION™ technology for steroid analysis and other clinical research applications.
(2) Innovations in microflow LC-MS to improve methods in clinical research and forensic toxicology applications.
1) Michael Jarvis, Technical Marketing Manager, Clinical Research - AB SCIEX
2) Evelyn McClure, MSc., Application Scientist - AB SCIEX

(1) Late-Breaking Updates from the MALDI Biotyper R&D group
(2) Clinical Impact of MALDI-TOF MS: Making MALDI Matter beyond the Lab
(3) GC-MS/MS: Applications for Routine Clinical and Emergency Toxicology
(1) Markus Kostrzewa, Ph. D. and VP for Clinical Research at Bruker Daltonics
(2) Christopher Doern, Associate Director of Microbiology at the VCU Medical Center
(3) Jennifer Colby, Ph. D., and Fellow of Clinical Chemistry and Toxicology at UCSF.

Join us for three short (about 15 minutes each) presentations by current Bruker users, followed by plenty of time Q&A, discussion and networking. All current Bruker users and those interested in Bruker Daltonics mass spectrometry products may attend. will present some late-breaking updates from the MALDI Biotyper R&D group. Prof. will speak on, “Clinical Impact of MALDI-TOF MS: Making MALDI Matter beyond the Lab.” And Jennifer Colby, Ph. D., and Fellow of Clinical Chemistry and Toxicology at the University of California, San Francisco will present on, “GC-MS/MS: Applications for Routine Clinical and Emergency Toxicology.”