Short Course : LC-MSMS 101 : Getting Started with Quantitative LC-MSMS in the Diagnostic Laboratory
Location: De Anza 2 (Portola Hotel > Ground Floor)
800
1200
Short Course : LC-MSMS 201 : Practical LC-MS/MS Method Development and Bioanalytical Method Validation for Clinical and Non-Clinical Samples
Location: Ironwood 2 (Portola Hotel > 3rd Floor)
800
1200
Short Course : LC-MSMS 203 : Validation of Quantitative LC-MS/MS Assays for Clinical and Academic Use
Location: De Anza 3 (Portola Hotel > Ground Floor)
Claire Knezevic, PhD
Johns Hopkins University
Dr. Claire Knezevic is an Assistant Professor in the Division of Clinical Chemistry at the Johns Hopkins University. She serves as director of Critical Care laboratories and the Drug Assay Laboratory at Johns Hopkins Hospital. She also serves as Assistant Director in the Clinical Pharmacology Analytical Laboratory. Her interests include all things small molecule, from toxicology to therapeutic drug monitoring and their impacts on clinical care.
Joshua Hayden, PhD, DABCC, FACB
Norton Healthcare
Joshua is currently the Chief of Chemistry at NortonHealthcare. He earned his PhD in chemistry from Carnegie Mellon University. He conducted postdoctoral research at Massachusetts Institute of Technology before completing a two-year clinical chemistry fellowship at University of Washington and 4 years as Assistant Professor at Weill Medical College. Joshua has special expertise developing and overseeing mass spectrometry assays in the clinical laboratory.
800
1200
Short Course : LC-MSMS 302 : Advanced LC-MS/MS Method Development, Method Troubleshooting and Instrument Operation Needed in Developing Successful Methods for Molecular identification and Quantitation in the Clinical Lab
Short Course : Data Science 101 : Breaking up with Excel: An Introduction to the R Statistical Programming Language
Location: Colton 1/2 (Conference Ctr > 2nd Floor)
800
1200
Short Course : Data Science 203 : Machine Learning : A Gentle Introduction
Location: Bonsai (Portola Hotel > Ground Floor)
800
1200
Short Course : Sample Preparation 201 : Sample Preparation and Alternative Matrices for LC-MS Assays
Location: Redwood 2 (Portola Hotel > 3rd Floor)
William Clarke, PhD, MBA, DABCC
Johns Hopkins University School of Medicine
Dr. Clarke received his Ph.D. in Analytical Chemistry from the University of Nebraska in Lincoln in 2000, followed by a post-doctoral fellowship in Clinical Chemistry at the Johns Hopkins School of Medicine, ending in 2002. In addition, he received an MBA focused on medical services management from the Carey School of Business at Johns Hopkins in 2007. Following his post-doctoral fellowship, he remained at Johns Hopkins, where he is a Professor in the Department of Pathology, as well as the director of Point-of-Care Testing, Reference Toxicology, and Phlebotomy for the hospital. He also serves as the Vice-Chair for Quality and Regulatory Affairs in the Department of Pathology. His research interests include clinical mass spectrometry, method development and evaluation for therapeutic drug monitoring, clinical toxicology, point-of-care testing, and development/validation of biomarkers for use in drug management. Dr. Clarke has published as author or co-author over 170 peer-reviewed manuscripts or book chapters, and is the Co-Editor of the textbook Contemporary Practice in Clinical Chemistry.
Mark Marzinke, PhD, DABCC, FAACC
Johns Hopkins University School of Medicine
Dr. Mark Marzinke is Professor of Pathology and Medicine in the Johns Hopkins University School of Medicine. He is board-certified in Clinical Chemistry by the American Board of Clinical Chemistry. He serves as the Director of the General Chemistry Laboratory at the Johns Hopkins Hospital and the Clinical Pharmacology Analytical Laboratory within the Division of Clinical Pharmacology. Dr. Marzinke is Co-Principal Investigator (PI) of the HIV Prevention Trials Network (HPTN) Laboratory Center (LC) and is the Director of the Clinical Laboratory Core for the Johns Hopkins Center for AIDS Research. His primary research interests are in the areas of antiretroviral pharmacology, HIV prevention science, mass spectrometry, pharmacogenetics and precision medicine, and laboratory automation. Dr. Marzinke has an active research program and serves as a principal investigator (PI) or co-investigator on a number of grants. He has collaborated on research to better characterize the multi-compartment pharmacology of antiretroviral agents when administered using alternative drug delivery systems using liquid chromatographic-mass spectrometric approaches. He has published more than 180 peer-reviewed articles, and holds leadership positions in several societies.
800
1200
Short Course : Metabolomics 102 : Microsampling and Mass Spectrometry – Fit for Purpose in the Clinical Screening and Monitoring Space
Location: Cottonwood 1 (Portola Hotel > 3rd Floor)
800
1200
Short Course : Clinical Proteomics 201 : Clinical Proteomics
Dr. Hoofnagle's laboratory focuses on the precise quantification of recognized protein biomarkers in human plasma using LC-MRM/MS. In addition, they have worked to develop novel assays for the quantification of small molecules in clinical and research settings. His laboratory also studies the role that the systemic inflammation plays in the pathophysiology of obesity, diabetes, and cardiovascular disease.
Cory Bystrom, PhD
Ultragenyx
Christopher Shuford, PhD
Labcorp
Chris Shuford, Ph.D., is Associate Vice President and Technical Director for research and development at Laboratory Corporation of America in Burlington, North Carolina. Chris received his B.S. in Chemistry & Physics at Longwood University and obtained his Ph.D. in Bioanalytical Chemistry from North Carolina State University under the tutelage of Professor David Muddiman, where his research focused on applications of nano-flow chromatography for multiplexed peptide quantification using protein cleavage coupled with isotope dilution mass spectrometry (PC-IDMS). In 2012, Chris joined LabCorp’s research and development team where his efforts have focused on development of high-flow chromatographic methods (>1 mL/min) for multiplexed and single protein assays for clinical diagnostics.
800
1200
Short Course : Clinical Proteomics 202 : MS-based Precision Diagnostics by Molecular Protein Analysis
Location: Ironwood 1 (Portola Hotel > 3rd Floor)
Renee Ruhaak, PhD
LUMC
Renee Ruhaak holds a PhD from the Leiden University Medical Center (LUMC, supervisor Prof. M. Wuhrer) and did a post-doc at UC Davis in the lab of Prof. C.B. Lebrilla prior to joining the department of Clinical Chemistry and Laboratory Medicine at the LUMC. She is currently an associate professor with a research focus on the application of mass spectrometry within the clinical setting. This entails both development and implementation of quantitative protein mass spectrometry, as well as the role of mass spectrometry in metrology and test standardization.
Mirjam Kruijt, MSc
LUMC
Mirjam is currently working as a 4th year PhD-student in the lab of prof.dr. Christa Cobbaert under the supervision of dr. Renee Ruhaak. Her focus is on the development of a new mass spectrometry test for quantitating antithrombin while simultaneously identifying antithrombin proteoforms by molecular characterization. The goal of this project is to improve patient diagnostics and advance the clinical care pathway for patients with hereditary antithrombin deficiency. Furthermore, the molecular characterization of antithrombin serves as a proof-of-concept for the simultaneous quantitative and qualitative characterization of any protein existing in multiple proteoforms using mass spectrometry.
Esther Reijnders, MSc.
LUMC
Esther is currently working as a 4th year PhD-student in the lab of prof. dr. Christa Cobbaert under the supervision of dr. Renee Ruhaak at Leiden University Medical Center in the Netherlands. Her research primarily focuses on evaluating the clinical effectiveness of a multiplex mass spectrometry-based apolipoprotein panel for cardiovascular risk prediction.
800
1200
Short Course : GlycoProteomics 101 : Clinical Glyco(proteo)mics by Mass Spectrometry
Location: Cottonwood 2 (Portola Hotel > 3rd Floor)
Tamas Pongracz, PhD
Leiden University Medical Center
Tamas obtained both his BSc and MSc degree at the University of Pécs, Hungary, where his work focused on the analysis of clinically relevant glycosylated proteins using capillary electrophoresis hyphenated to mass spectrometry.
In 2018 – after a 3-month Erasmus internship – he moved to the Netherlands, where after concluding his PhD, he became a PostDoc working under the supervision of Manfred Wuhrer at Leiden University Medical Center. His projects focus on clinical glycomics in various disease settings, such as fibrotic and autoimmune liver diseases, kidney transplantation and COVID-19, as well as on technological developments in the field of linkage-specific sialic acid derivatization.
Guinevere Lageveen-Kammeijer, PhD
University of Groningen
Guinevere received her PhD on exploring prostate-specific antigen (PSA), the well-known biomarker for prostate cancer, and its glycosylation by capillary electrophoresis and mass spectrometry. Since 2022, Guinevere is appointed as an Assistant Professor (tenure track) in the Analytical Biochemistry group at the Univeristy of Groningen She currently works on further expanding a mass spectrometry-based PSA glycosylation assay which she developed during her PhD. In addition, she explores the possibilities for the in-depth analysis of glycans and intact glycoproteins for biomarker discovery for other diseases as well as for the characterization of biopharmaceuticals. In 2017, Guinevere joined the organization committee of the Netherlands Area Biotech (NLab) Discussion group of CASSS. In 2019, she became a member of the scientific committee of the glycomics session, and a member of the early career committee, of MSACL EU. Her research interests are focused on bringing together researchers from the field of biomarker discovery with clinical laboratory professionals, ensuring a better translation of potential biomarkers to the clinic. Moreover, she is dedicated to convincing her fellow colleagues that glycosylation is an important subject and should not be neglected just because it is rather complicated.
Short Course : LC-MSMS 101 : Getting Started with Quantitative LC-MSMS in the Diagnostic Laboratory
Location: De Anza 2 (Portola Hotel > Ground Floor)
1400
1800
Short Course : LC-MSMS 201 : Practical LC-MS/MS Method Development and Bioanalytical Method Validation for Clinical and Non-Clinical Samples
Location: Ironwood 2 (Portola Hotel > 3rd Floor)
1400
1800
Short Course : LC-MSMS 203 : Validation of Quantitative LC-MS/MS Assays for Clinical and Academic Use
Location: De Anza 3 (Portola Hotel > Ground Floor)
1400
1800
Short Course : LC-MSMS 302 : Advanced LC-MS/MS Method Development, Method Troubleshooting and Instrument Operation Needed in Developing Successful Methods for Molecular identification and Quantitation in the Clinical Lab
Short Course : Data Science 101 : Breaking up with Excel: An Introduction to the R Statistical Programming Language
Location: Colton 1/2 (Conference Ctr > 2nd Floor)
1400
1800
Short Course : Data Science 201 : Flexing with R : Databases to Dashboards
Location: Colton 3 (Conference Ctr > 2nd Floor)
Shannon Haymond, PhD
Northwestern University Feinberg School of Medicine
My lab performs research and clinical testing using mass spectrometry methods, develops new assays, and applies data analytics to enable improved quality and efficiency. My computational pathology efforts are aimed at building the capacity for advanced data analytics in the department through innovations in infrastructure, education, and research to facilitate data-informed decision making for clinical care, operations, and quality assurance.
Patrick Mathias, MD, PhD
University of Washington
Patrick Mathias, M.D., Ph.D., is a board-certified clinical pathologist and Associate Director of Informatics for UW Laboratory Medicine.
Lab medicine has large impact on the general practice of medicine. It is key to correctly diagnosing diseases and selecting the right treatments for patients. Dr. Mathias's goal is to combine technical and medical knowledge to fulfill the triple aim--reduce the per capita cost of health care, improve the health of populations and most importantly improve the patient experience of care.
Dr. Mathias earned his M.D. and Ph.D. from the University of Illinois. His clinical and research interests include clinical informatics, clinical chemistry and molecular diagnostics.
1400
1800
Short Course : Data Science 203 : Machine Learning : A Gentle Introduction
Location: Bonsai (Portola Hotel > Ground Floor)
1400
1800
Short Course : Sample Preparation 201 : Sample Preparation and Alternative Matrices for LC-MS Assays
Location: Redwood 2 (Portola Hotel > 3rd Floor)
1400
1800
Short Course : Metabolomics 203 : Practical Bioinformatics and Statistics in Metabolomics
Location: Cottonwood 1 (Portola Hotel > 3rd Floor)
Tim Garrett, PhD
University of Florida College of Medicine
Dr. Garrett has over 20 years of experience in the field of mass spectrometry spanning both instrument and application development. He received his PhD from the University of Florida, under Dr. Richard A. Yost, working on the first imaging mass spectrometry-based ion trap instrument. He has also developed MALDI-based approaches to analyze proteins in bacteria and small molecules in tissue specimens. His current interests include the translation of LC-HRMS, MALDI, DESI and LMJSSP in metabolomics to clinical diagnostics. He is an Associate Professor in the Department of Pathology at the University of Florida, and an Associate Director for the Southeast Center for Integrated Metabolomics (SECIM).
1400
1800
Short Course : Clinical Proteomics 201 : Clinical Proteomics
Short Course : Clinical Proteomics 202 : MS-based Precision Diagnostics by Molecular Protein Analysis
Location: Ironwood 1 (Portola Hotel > 3rd Floor)
1400
1800
Short Course : Lipidomics 101 : Mass Spectrometry-based Lipidomics and Clinical Applications
Location: Redwood 1 (Portola Hotel > 3rd Floor)
Anne K. Bendt, PhD
Singapore Lipidomics Incubator (SLING), National University of Singapore
Anne K Bendt studied Biology focusing on marine biotechnology (Greifswald University, Germany), followed by a PhD in Biochemistry (Cologne University, Germany) employing proteomics and transcriptomics. Driven by her fascination for infectious diseases, she joined the National University of Singapore (NUS) in 2004 to develop lipidomics tools for tuberculosis studies. She is now a Principal Investigator at the Life Sciences Institute, NUS, focussing on translation of mass spec technologies into clinical applications, and serving as the Deputy Director of the Singapore Lipidomics Incubator (SLING) taking care of operations and commercialization.
Amaury Cazenave Gassiot, PhD
Singapore Lipidomics Incubator (SLING) and Department of Biochemistry, National University of Singapore
Research Assistant Prof. Cazenave-Gassiot is an early-career researcher and an expert in mass spectrometry-based lipidomics. He graduated with a PhD in analytical chemistry at the University of Southampton (UK), under the supervision of Dr John Langley, specialising in supercritical fluid chromatography and mass spectrometry. His interest in lipids started while a postdoc in the team of Professor Anthony Postle, still in Southampton. A member of SLING since 2009, his research centres on separation sciences, mass spectrometry, and their applications to life sciences, especially lipid biochemistry. He has developed chromatographic and mass spectrometric methods for the identification and quantification of lipids in diverse biological systems. This has included successful local and international collaborations.
Michael Chen, M.D., C.M.
University of British Columbia
Prof. Michael Chen is a Clinical Assistant Professor at the University of British Columbia. He completed his M.D., C.M. undergraduate medical program from McGill University in 2011. His journey at UBC began with the appointment as Adjunct Assistant Professor in the Division of Medical Sciences in 2017. Since 2019 he has been a Medical Director at Victoria Lipid Clinic. Most recently, he is contributing to the UBC COVID-19 Clinical Research Coordination Initiative as Co-Chair of the biobank. His research interests are Clinical and Translational Proteomics, Biomarker validation and Clinical Biobanking.
1400
1800
Short Course : GlycoProteomics 101 : Clinical Glyco(proteo)mics by Mass Spectrometry
Location: Cottonwood 2 (Portola Hotel > 3rd Floor)
