Translating Pre-Clinical Research to Clinical Patient Care™



Job Posting

Mass Spectometry Specialist

Company:Providence Health, St. Paul's Hospital
Location:Vancouver, British Columbia
Position:Mass Spectometry Specialist


Mass Spectometry Specialist, Clinical Lab Administration - St. Paul’s Hospital

Provincial Laboratory Medicine Services (PLMS)

Vancouver, BC

The Mass Spectrometry Specialist will be responsible for the development and maintenance of small molecule and protein assays for patient testing on the SCIEX triple quadrupoles (5000, 5500, 6500) coupled to high performance liquid chromatography (LC) and multiplexing systems (Shimadzu); sample preparation is automated on Hamilton Startlet liquid handler. The Mass Spectrometry Specialist is solely responsible for ground up LC mass spectrometry assay development work, which is highly specialized and requires knowledge of use, troubleshooting, and maintenance of liquid chromatography instruments, triple quadrupole mass spectrometers, and robotic liquid handling systems.

What you’ll do:

Lead, through hands-on work, mass spectrometry assay development projects and all modifications to existing assays including data interpretation, troubleshooting and optimization of sample preparation and experimental design, quality procedures and assays.
Support, train, and provide technical advice and direction to LC-MS/MS users, including Medical Laboratory Technologists (MLTs), Students, Medical Residents, Fellows, Clinical Chemists, Medical Biochemists and all other new and existing personnel using the equipment in all aspects of their routine work and in newly-validated methods.
Sources and chooses appropriate reagents for assay development (e.g., chemical, standards, calibrators, internal standards).
Program and troubleshoot the liquid handler and trains MLTs and other users on its operation.
Develops and optimizes method parameters (e.g., compound-optimization experiments, chromatographic condition selection and optimization).
Researches and develops novel mass spectrometric methods.
Stays apprised of new technologies for sample preparation and analysis (e.g., new chromatographic techniques, new automation tools, and new MS approaches).

What you bring:

A level of education, training, and experience equivalent to a master’s degree (or PhD) in a relevant discipline
A minimum five (5) years’ experience which may include a portion of graduate studies, periods of which involved substantial hands-on LC-MS/MS time, preferably with SCIEX instruments and software.
Familiarity with CLSI guidelines and DAP accreditation is an asset.
You also have:

Demonstrated ability to evaluate experimental results and provide direction to personnel.
Demonstrated ability to work independently.
Ability to communicate effectively with all levels of faculty, staff and trainees through both oral and written communication.
Proven ability to manage and monitor operations to effectively resolve problems, challenges or issues.
Ability to exercise tact, diplomacy discretion, considerable judgement, and possess initiative, and a strong sense of responsibility.
Occasional travel required.
Awareness of and commitment to learning and understanding the Truth & Reconciliation Commission’s 94 Calls to Action (2015), In Plain Sight Report (2020), BC's Declaration on the Rights of Indigenous Peoples Act (2019), and other related reports.
Commitment to upholding the shared responsibility of creating lasting and meaningful reconciliation in Canada as per TRC (2015) and BC's Declaration on the Rights of Indigenous Peoples Act (2019).
As a strong asset for consideration, we are looking for our successful candidate to have: Knowledge of social, economic, political and historical realities impacting indigenous communities and familiarity with Indigenous Cultural Safety and anti-racism and accompanying reports (BC DRIPA, TRC, etc.).

What we bring:

Every PHSA employee enables the best possible patient care for our patients and their families. Whether you are providing direct care, conducting research, or making it possible for others to do their work, you impact the lives of British Columbians today and in the future. That’s why we’re focused on your care too – offering health, wellness, development programs to support you – at work and at home.

Join one of BC’s largest employers with province-wide programs, services and operations – offering vast opportunities for growth, development, and recognition programs that honour the commitment and contribution of all employees.
Access to professional development opportunities through our in-house training programs, including +2,000 courses, such as our San’yas Indigenous Cultural Safety Training course, or Core Linx for Leadership roles.
Enjoy a comprehensive benefits package, including municipal pension plan, and psychological health & safety programs and holistic wellness resources.
Annual statutory holidays (13) with generous vacation entitlement and accruement.
PHSA is a remote work friendly employer, welcoming flexible work options to support our people (eligibility may vary, depending on position).
Access to WorkPerks, a premium discount program offering a wide range of local and national discounts on electronics, entertainment, dining, travel, wellness, apparel, and more.

For more information or to apply follow this link: